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Baricitinib Tablets: Uses, Efficacy & Complications

Baricitinib is a targeted therapy drug. The medicine is sold under the brand name Olumiant. It belongs to the category of Janus kinase inhibitors. This medicine is approved by the US FDA for the treatment of rheumatoid arthritis. Recently, it has also received approval for Alopecia Areata and COVID-19 Infection treatment. It is also considered an effective disease-modifying antirheumatic drug (DMARD)

Active ingredients: Baricitinib

Inactive ingredients: Ferric oxide, titanium dioxide, croscarmellose sodium, polyvinyl alcohol, magnesium stearate, polyethylene glycol, microcrystalline cellulose, and mannitol

Baricitinib Uses 

Olumiant was first approved by the US FDA for rheumatoid arthritis in May 2018. Further, it was studied for conditions like alopecia areata and coronavirus infection. 

Rheumatoid Arthritis

This type of arthritis is an inflammatory disorder. It can also be listed under the category of autoimmune diseases. Rheumatoid Arthritis directs the immune system to attack the normal cell of the body. This causes inflammation and pain. Baricitinib tablets are prescribed to treat patients diagnosed with rheumatoid arthritis that is moderately to severely active. This drug is specifically indicated for use in patients who have shown an irrelevant response after the use of tumor necrosis factor blockers. 

COVID-19 Infection

Coronavirus disease is a viral infection caused by the virus SARS-CoV-2. This disease affects people in varied ways. During the pandemic, certain patients required hospitalization for treatment. Recently, Olumiant has been approved for use in patients suffering from COVID-19 Infection in hospitalized patients aged above 18 years. The drug is expected to manage the condition in people who require any of the following.

  • Invasive mechanical ventilation
  • Non-invasive mechanical ventilation
  • Extracorporeal membrane oxygenation

Alopecia Areata

It is also an autoimmune disease like arthritis. Alopecia Areata causes patchy hair loss having no or unpredictable reason. The patches can be one or more in patients. Olumiant tablet is indicated for systemic treatment of this condition. Plus, this medicine is expected to treat or reduce the signs of hair loss in the entire body.

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